Chang (April) Shu

Principal Investigator


Dr. Chang Shu, also known as April Shu, is an Assistant Professor in the Center for Genetic Epidemiology and the Department of Population and Public Health Sciences as well as Department of Pediatrics at Keck School of Medicine of USC. April specializes in psychiatric genetics and epidemiology. Her work focuses on autism genetics, substance use epigenetics, and single-cell transcriptomics. She utilizes advanced statistical and machine learning tools to uncover novel genetic factors in mental and behavioral disorders.
April earned her Ph.D. in Mental Health focusing on psychiatric genetics and epigenetics in 2018 from Johns Hopkins Bloomberg School of Public Health under the mentorship of Drs. Brion Maher and Dani Fallin. During her time there, she also trained in statistical genetics and machine learning with Dr. Hongkai Ji and completed a concurrent master's degree in Biostatistics. Her postdoctoral training was conducted at Yale University with Dr. Ke Xu, followed by a position as an Associate Research Scientist in labs led by Drs. Wendy Chung and Yufeng Shen. She holds an additional master's degree in Epidemiology from Harvard School of Public Health, mentored by Drs. Edward Giovannucci and Benjamin Le Cook. April completed her undergraduate degree in Chemistry and Biochemistry at Tsinghua University in Beijing.
April's interdisciplinary training positions her uniquely at the intersection of genetics, epidemiology, and biostatistics, offering a comprehensive lens to explore complex mental health issues.

Qing Tan

Postdoctoral Associate


Qing is a Postdoctoral Associate in the Center for Genetic Epidemiology at USC. He completed his Ph.D. in Computational Mathematics at Wuhan University, China. As a researcher in mathematical methods and bioinformatics, he specializes in using mathematical models to design machine learning algorithms for integrative analysis of multi-dimensional data, particularly in single-cell RNA-seq , spatial transcriptomics, and, imaging, and clinical data. During his Ph.D., he primarily conducted integrative analyses of imaging and clinical data of endometrial cancer patients from the perspective of evolutionary network models. Additionally, he designed early warning models for acute kidney injury based on machine learning algorithms.

Wanyi Tang

PhD Student in Epidemiology


Wanyi is a PhD student in Epidemiology in the Department of Population and Public Health Sciences at USC. She currently focuses on examining the underlying epigenetic mechanisms beyond Organophosphorus Flame Retardants (OPFR) and maternal depression. She earned her Master of Public Health in Applied Biostatistics and Epidemiology from the joint degree program between Yale University and Tsinghua University.

Jingyu Xie

PhD Student in Epidemiology


Jingyu is a PhD student in Epidemiology in the Department of Population and Public Health Sciences at USC. She currently focues on unraveling the genetic and phenotypic heterogeneity in Autism Spectrum Disorder to inform precise subtyping and personalized medicine. She earned her Master of Epidemiology and Biostatistics degree from the Chinese University of Hong Kong.

Boyang Li

PhD Student in PIBBS


Boyang Li is a fourth year PhD student in the Biomedical and Biological Sciences (PIBBS) program co-mentored by Dr. Hussein Yassine at the USC. He currently focuses on the role of lipid dysregulation and cellular senescence in Alzheimer's Disease pathologies from single cell RNA-seq data. He earned his bachelor degree from the University of California, Irvine.

James Lee

Master's Student in Biostatistics


James is a first year master’s student in Biostatistics at USC with a background in Biotechnology. His research interests include the application of AI and computational biology to address public health challenges. In his previous work, he developed a Python-based pipeline for ChIP-Seq data analysis. He is passionate about leveraging biostatistics and AI to explore health disparities and enhance preventive healthcare strategies.

Nithin Aditya Pradeepkumar

Master's Student in Computer Science


Nithin is a first-year M.S. student in Computer Science at USC. His research focuses on applying machine learning to healthcare. His previous research involved developing a resource-efficient pipeline for blood pressure estimation using PPG signals, leveraging EdgeML techniques. He is passionate about exploring the intersection of machine learning and healthcare.

Previous trainees

Qi Zhang: MS graduate in Biostatistics at USC
Emily Lu: Research Assistant at USC
Preethi Prakash: BS graduate in Computer Science at Columbia University